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NestoPure
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  • NestoPure
  • NestoPure

NestoPure Protein Purification System

Next-generation integrated sample pump laboratory-grade chromatography system, compact with low dead volume. Designed for rapid process development and optimization.
  • Product Introduction
  • Product Parameters
  • Related Documents

    The NestoPure next-generation chromatography system integrates a sample pump and pH valve, featuring a more compact design that significantly reduces flow path dead volume. The system can be equipped with a titanium alloy pump head, offering enhanced corrosion resistance and biocompatibility. Additionally, the conductivity detector is equipped with an insulated housing to effectively reduce the interference of external temperature fluctuations on conductivity measurements. When paired with the new NestoPure SC sample collection system, it enables continuous processes for multi-step chromatography.

    The accompanying Unique CDSystem chromatography workstation is comprehensive in functionality and outstanding in performance, integrating instrument control, method management, data analysis, standard curve plotting, report editing, user permission management, audit tracking, digital signatures, and web-based databases. This workstation meets regulatory requirements such as FDA 21CFR Part 11, GLP, and GMP.

     

    Features:

    ● High-Precision Pump: Configured for accurate performance.

    ● High Level of Automation: Capable of unattended operation.

    ● Integrated Sample Pump and pH Valve: More compact design.

    ● Optional Titanium Alloy Pump Head: Enhanced corrosion resistance and biocompatibility.

    ● Compatible with Various Collectors or Integrated Sample Collection Systems: Flexible options for collection needs.

    ● Stylish Appearance: Ergonomically designed for ease of maintenance and upkeep.

     

  • Configuration

    Product Name

    Technical Specifications

     

    Standard Configuration

    Infusion Pump

    NestoPure25

    NestoPure100

    NestoPure150

    NestoPure300

    Dual Pump System

    Flow Rate Range: 0.001-25 ml/min

    Pressure Range: 0-27.5 MPa (4000 psi)

    Flow Accuracy: ±1.2%

    Dual Pump System

    Flow Rate Range: 0.01-100 ml/min

    Pressure Range: 0-10 MPa (1500 psi)

    Flow Accuracy: ±1.2%

    Dual Pump System

    Flow Rate Range: 0.01-150ml/min

    Pressure Range: 0-5MPa

    (725psi)

    Flow Accuracy: ±1.2%

    Dual Pump System

    Flow Rate Range: 0.1-300ml/min

    Pressure Range: 0-3.5MPa

    (500psi)

    Flow Accuracy: ±1.2%

    Flow Rate Repeatability: RSD ≤ 0.5%

    Gradient Type: Linear, Isocratic, Step Gradient

    Automatic Sample Injection Valve

    Three-Position Seven-Port Valve,Software-Controlled Reverse Control,Supports Quantitative Sampling,Supports Load, Inject, Waste Functions.

    Fixed Wavelength Detector

    LED Light Source,Fixed Wavelength,Lifetime ≥ 8000 Hours

    Temperature Sensor

    Reading Range: 0-100°C,Temperature Compensation for Conductivity and pH

    Conductivity Detector

    Display Range: 0.001-999.99 mS/cm, Includes Temperature Compensation.

    Back Pressure Valve

    20psi(2ml/min)

    Online Filter

    20 μm Titanium Alloy Filter

    Dynamic Mixer

    OptionL 0.6 ml, 2 ml, or 5 ml mixed 

    Chromatography Column Clamp

    2 pcs

    Startup Package

    Startup Package (Including Tubing, Connectors, Maintenance Tools, Manual, Dongle, etc.)

    Control System

    Unique CDSytem chromatograghy software (Without Computer)

     

    Product Name

    Technical Specifications

    pH Detector

    Display Range: pH 0-14, Detection Range: 2-12, Accuracy: ±0.1; Includes Temperature Compensation

    pH Valve

    The pH Valve has 5 Operating Modes: Back Pressure Mode, pH Detection Mode, Back Pressure + pH Detection Mode, pH Calibration/Protection Mode, Direct Discharge Mode. Calibration and saving of the pH meter can be performed without disassembly.

    Bubble Sensor

    Used to monitor sample loading and detect bubble generation within the system; bubble sensors are located at A, B inlets and the sample inlet.

    Buffer Inlet Valve

    A/B Pumps can be equipped with 2, 6 (for 300 system), 8, or 10-channel inlet valves.

    UV Detector

    L2 Fixed Dual Wavelength: Detection Range 280 nm and 260 nm.
    DAD402 Variable Dual Wavelength: Detection Range 200-400 nm, Full Spectrum Direct Reading, can simultaneously detect two arbitrary wavelengths.

    DAD604 Variable Quadruple Wavelength: Detection Range 200-600 nm, Full Spectrum Direct Reading, can simultaneously detect four arbitrary wavelengths.

    DAD804 Full Wavelength Detection: Detection Range 200-800 nm, Full Spectrum Direct Reading, can simultaneously detect four arbitrary wavelengths.

    DAD894 Full Wavelength Detection: Detection Range 190-800 nm, Full Spectrum Direct Reading, can simultaneously detect four arbitrary wavelengths.

    Outlet Valve

    Optional 2, 8, or 10-channel large volume collection valves.

    Component Collector

    Frac-01 supports sample collection from 96-well plates up to a maximum of 300 ml, standard with one collection rack (supports 96-well plates or various centrifuge tubes and test tubes).

    Frac-02 supports sample collection from 96-well plates up to a maximum of 300 ml, standard with two collection racks (supports 96-well plates or various centrifuge tubes and test tubes).

    Frac-02P supports sample collection from 96-well plates up to a maximum of 300 ml, standard with two collection racks (supports 96-well plates or various centrifuge tubes and test tubes).

    Frac-02C supports sample collection from 96-well plates up to a maximum of 300 ml, standard with two collection racks (supports 96-well plates or various centrifuge tubes and test tubes).

    Column Position Valve

    Single Column Valve, supports Forward/Reverse/Bypass.

    Three-Position Valve, can connect three chromatographic columns and Bypass simultaneously, each position supports Forward and Reverse Flushing.

    Six-Position Valve, can connect six chromatographic columns and Bypass simultaneously, each position supports Forward and Reverse Flushing.

    Pressure Monitoring

    Pre-column Pressure Monitoring.

    Pre-column and Post-column Pressure Monitoring.

    Sample Pump

    SP25,Flow Rate Range: 0.001-25 ml/min, Pressure Range: 0-27.5 MPa, Flow Rate Accuracy: ±1.2%.

    SP100,Flow Rate Range: 0.01-100 ml/min, Pressure Range: 0-10 MPa, Flow Rate Accuracy: ±1.2%.

    SP150,Flow Rate Range: 0.01-150 ml/min, Pressure Range: 0-5 MPa, Flow Rate Accuracy: ±1.2%.

    SP300, Flow Rate Range: 0.1-300 ml/min, Pressure Range: 0-3.5 MPa, Flow Rate Accuracy: ±2%.

    Sample Inlet Valve

    Optional 2, 6, 8, or 10-channel inlet valves.

  • Protein Purification System-NestoPure.pdf   

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