Fully automatic lab scale tangential flow filtration system, with automatic TMP optimization and dialysis point optimization functions, best tool for process development, process characterization, filter lifetime testing, etc.

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Crossflow Filtration

Lab-scale Crossflow Filtration System

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- Commodity name: AutoTFF075
- 产品系列: Crossflow System
Fully automatic lab scale tangential flow filtration system, with automatic TMP optimization and dialysis point optimization functions, best tool for process development, process characterization, filter lifetime testing, etc.

Unique AutoTFF075 is a flexible and automated lab scale crossflow filtration system that can be used with hollow fibers or cassette filters for concentration, diafiltration or clarification of samples. It is widely used in biological product process, such as antibodies, recombinant proteins, mRNA, nucleic acids, viral vectors, etc. Its flexible configuration allows for manual operation and highly automated process control. Combined with a powerful intuitive management system, it is suitable for TFF process development, scale up study, and sample preparation

Features
● Automatic TMP control, weighing, feeding, precise control of concentration ratio and diafiltration volume.
● Compact design, small recirculation volume, to meet high concentration requirements.
● The User friendly control software offers easily recipe setup, operation control, data recording and user management.
● Optional permeate pump for comprehensive microfiltration process control.
● High automation with pre-defined method modules, recipe and recipe sequence.
● Optional conductivity sensor, pH, UV, for comprehensive process monitoring.
● Adapt to different type of cassette filters and hollow fibers.

Three models available for flexible selection.

Unique AutoTFF075-L: Peristaltic Pump Basic Version
Unique AutoTFF075-M: Peristaltic Pump version with multiple options
Unique AutoTFF075-MD: Diaphragm Pump version with multiple options

General Parameters

Dimensions(LxDxH,mm)	580 x 355 x 640 (filter holder not included)
Power Supply	240VAC, 50-60Hz
Weight	48kg(include 0.1m² filter holder)
Power	160W
System Language	Chinese, English
Ambient Temperature	2-35°C

System Parameters

Filtration area	50cm²- 0.1m²(The specific filtration area can be varied with different filters)
Maximum feed pressure	5bar
Minimum recirculating volume	20ml (when using standard tubing）
Process temperature	2-50°C
Feed pump flow rate	0-700ml/min （(Max flowrate 1200ml/min with 25#tubing)）
Transfer pump flow rate	0-600ml/min
Permeate pump flow rate	0-300ml/min
Recirculation vessel volume	A 1000ml circulating vessel comes standard, with 50ml, 250ml, and 500ml vessel available as options
Stirring speed	0-300rpm
Pressure sensor	Detection range: 0-5 Bar
Conductivity sensor	Detection range:0.001-999.99ms/cm
Temperature sensor	Integrated in conductivity sensor, detection range: 0-99 ° C
pH	Detection range: 0-14
Retentate and filtration weighing	0-6kg
Filter holder	1 ABS multifunctional holder for 50cm ² Capsule capsule or hollow fiber filters with a diameter no more than 50mm 1 0.1m ² Stainless steel holder; Designed to hold 1 to 5 standard filter
Tube&Connector	Luer Lock

Crossflow System-AutoTFF075.pdf

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Unique AutoTFF075-L: Peristaltic Pump Basic Version	Unique AutoTFF075-M: Peristaltic Pump version with multiple options	Unique AutoTFF075-MD: Diaphragm Pump version with multiple options