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AutoOligo25/100/150
AutoOligo25/100/150
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  • AutoOligo25/100/150
  • AutoOligo25/100/150

AutoOligo25/100/150 Oligonucleotides Synthesizer

Laboratory-scale oligonucleotides synthesizer, utilizing solid-phase synthesis method for rapid synthesis of oligonucleotides samples ranging from 10 μmol to 12 mmol.
  • Product Introduction
  • Product Parameters
  • Related Documents

    Unique AutoOligo® is a flexible and intuitive fully automated oligonucleotide synthesizer designed for the rapid synthesis of oligonucleotides samples ranging from 10μmol to 12 mmol. It is suitable for clinical research, pharmaceutical development, and the synthesis of molecular diagnostic probes.

    The Unique AutoOligo® features a high-precision metering pump drive system that is compatible with reagents used in oligonucleotides synthesis. Utilizing flow-through solid-phase synthesis technology, it significantly reduces reagent consumption while ensuring control over reaction speed and contact time. This results in higher synthesis efficiency and facilitates linear amplification, achieving both cost-effectiveness and high-quality synthesis results.

    The Unique AutoOligo® can simultaneously utilize up to 12 different amidites, automatically executing the synthesis process on a single column.

    The Unique CDSystem workstation comes equipped with a powerful data management system, providing a complete and reliable platform for oligonucleotides synthesis method development.

     

    Features:

    ● High-precision metering pump, compatible with organic reagents.

    ● High degree of automation with low reagent consumption.

    ● User-friendly software interface with flexible method editing.

    ● Sequential synthesis.

    ● High capacity: 20 minutes to complete a synthesis cycle.

    ● Online monitoring of UV, conductivity signals, and pressure.

    ● Amidites solution recirculation.

    ● Complies with FDA and USP regulatory requirements.

  • Parameters(AutoOligo®25-150)

    Chemical solvent compatibility

    Compatible with commonly used reagents for DNA and RNA synthesis, including acetonitrile, coupling reagents, deprotection agents, oxidizing agents, cap agents, and thio reagents (not compatible with tetrahydrofuran).

    Synthesis scale

    10μmol-12mmol

    Synthesis efficiency

    >99% for DNA >98% for RNA

    Cycle time

    4.5 to 25 minutes (standard DNA)

    Dimensions(WxHxD)

    400x550x480mm

    Weight

    60kg

    Pump

    2 piston pumps

    Synthesis column

    1 pc

    Number of inlets

    Standard 8, maximum 12

    Pump speed

    Oligo25:2x25ml/min
    Oligo100:2x100ml/min
    Oligo150:2x150ml/min

    Detector

    Conductivity, UV detector,UV detector wavelength range: 200-600 nm, 4 channels

    System protection

    Argon or nitrogen

    Inlet pressure

    0.3-0.35bar

    Valve

    7 low dead volume valves

    Control system

    Unique CDSystem

    Warranty

    1 year

  • AutoOligo25/100/150 Oligonucleotides Synthesizer

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