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AutoOligo600
AutoOligo600
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  • AutoOligo600
  • AutoOligo600

AutoOligo600 Oligonucleotides Synthesizer

The AutoOligo600 Oligonucleotides Synthesizer is a pilot-scale oligonucleotides synthesis instrument that meets GMP requirements and can synthesize oligonucleotides samples ranging from 1 mmol to 50 mmol.
  • Product Introduction
  • Product Parameters
  • Related Documents

    The AutoOligo®600 is a flexible and intuitive fully automated oligonucleotide synthesizer, covering a range of 1 mmol to 50 mmol, designed to meet the needs for batch production of gram-scale products. It is suitable for oligonucleotide synthesis in early to mid-stage clinical trials.

    The AutoOligo®600 utilizes a high-precision metering pump drive system, compatible with reagents for oligonucleotides synthesis, employing flow-through solid-phase synthesis technology. This significantly reduces reagent consumption while ensuring control over reaction speed and contact time. It also enhances synthesis efficiency, facilitating linear scaling to achieve high cost-effectiveness and high-quality synthesis results.

    The AutoOligo®600 can simultaneously use up to 19 different amidites, automatically executing the synthesis process on a single column.

    The unique CDSystem workstation features a powerful data management system, providing a complete and reliable platform for nucleic acid synthesis method development.

     

    Features:

    ● Three High-Precision Metering Pumps: Capable of withstanding organic reagents.

    ● Flexible Configuration Options: Customized to meet specific requirements.

    ● Overpressure Explosion-Proof Design: Ensures safe operation.

    ● Compliance: Meets FDA and USP regulatory requirements.

    ● User-Friendly Software Interface:  flexible method editing.

    ● High Capacity: 20mins to complete a synthesis cycle 

    ● Online Monitoring:  UV, conductivity signals, and pressure.

    ● Reagent Solution Recirculation: Enhances efficiency and resource utilization.

  • Parameters(AutoOligo®600)

    Synthesis Scale

    1mmol-50mmol

    Dimensions(WxHxD)

    1200*1750*700mm

    Pump Type

    Plunger Pump

    Number of Pumps

    3

    Maximum Pump Pressure

    20bar

    Operating Flow Rate

    4-1200ml/min

    Pressure Flow Rate Control

    Yes

    Linear Flow Rate Control

    Yes

    Valves

    9 (Expandable to 11)

    Number of Inlets

    11 (Expandable to 19)

    Number of Solvent Inlets

    8 pc

    Number of Column Positions

    1 pc

    Post-Column Pressure:

    1 pc

    Post-Column UV Detector

    1 pc

    Conductivity Temperature Integration Module

    1 pc

    Number of Outlets

    4 pc

    External Communication Interface

    2 pc

    Gas Supply Module

    1 pc

    External Gas Input Pressure

    5-7 bar

    Equipment Gas Input Pressure

    2-3 bar

    Liquid Line Material

    FFKM/PEEK/FEP

    Frame, Cabinet, and Support Material

    Stainless Steel

    Explosion Protection Level

    EX pz Ⅱ B T4 Gc

  • Oligonucleotides Synthesizer-AutoOligo

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