PSphase-HDmicro Solid Phase Support
Belonging Category:
- Product Introduction
- Product Parameters
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The synthesis of oligonucleotides primarily employs the chemical phosphoramidite triester method and solid-phase support. Commonly used immobilized surfaces include Controlled Pore Glass (CPG) or Polystyrene (PS) beads. The loading capacity of Controlled Pore Glass (CPG) supports is limited, approximately 50-90 μmol/g. The PSphase-HDmicro solid-phase support launched by InSaS utilizes polymerization technology to synthesize fixed cross-linking PS microspheres, offering higher loading capacities (up to 250 μmol/g for RNA synthesis and 400 μmol/g for DNA synthesis). It also features superior swelling ratios, uniform coverage of surface groups, and good inter-batch stability.
Advantages of PSphase Solid Phase Support:
● Compatibility: Compatible with standard reagents and adaptable to various synthesis conditions.
● Standard DMT Groups: Meets standard DMT group and deprotection conditions.
● Reproducibility: Excellent product reproducibility.
● Cost-Effectiveness: Offers outstanding cost-performance ratio.
Application Fields:
Primarily used in laboratory and commercial production for solid-phase synthesis of ASO, siRNA, sgRNA, and others.
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Performance and Parameters of Solid Phase Support
Solid Phase Support Packaging Specifications
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